4-chloro-3-trifluoromethylphenyl isothiocyanate - Names and Identifiers
4-chloro-3-trifluoromethylphenyl isothiocyanate - Physico-chemical Properties
Molecular Formula | C8H3ClF3NS
|
Molar Mass | 237.63 |
Density | 1.47g/mLat 25°C(lit.) |
Melting Point | 34 °C |
Boling Point | 248-251°C(lit.) |
Flash Point | 248-251°C |
Specific Gravity | 1.440 |
BRN | 787371 |
Storage Condition | Keep Cold |
Sensitive | Stench |
Refractive Index | n20/D 1.5905(lit.) |
4-chloro-3-trifluoromethylphenyl isothiocyanate - Risk and Safety
Risk Codes | 34 - Causes burns
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27 - Take off immediately all contaminated clothing.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
UN IDs | UN 3265 8/PG 2 |
WGK Germany | 3 |
HS Code | 29309090 |
Hazard Note | Harmful/Stench |
Hazard Class | 6.1 |
Packing Group | III |
4-chloro-3-trifluoromethylphenyl isothiocyanate - Introduction
isothiocyanate is an organic compound with the chemical formula CF3C6H3ClNCS. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless or light yellow liquid
-Density: 1.53g/cm3
-Boiling Point: 132-133 ° C
-Melting point: 50-52 ° C
-Solubility: Soluble in organic solvents such as ethanol, ether and dichloromethane, insoluble in water
Use:
-As a chemical reagent: used in the thiolation reaction in organic synthesis reactions, the isothiocyanate functional group on the benzene ring can be introduced.
-As an intermediate: The compound can be used to synthesize other organic compounds, such as drugs, pesticides, etc.
Method:
-It can be prepared by the reaction of 4-chloro-3-trifluoromethylbenzene with ethyl thioisocyanate. The reaction conditions are that 4-chloro-3-trifluoromethylbenzene and ethyl thioisocyanate are reacted in ether or methylene chloride solution in a dry environment, and after a period of time, the product is obtained.
Safety Information:
-The compound is irritating to the skin and eyes. Pay attention to wearing protective gloves and goggles during operation.
-Avoid inhaling its vapor or dust and operate in a well-ventilated place.
-Avoid direct sunlight when storing, keep it sealed, away from heat sources and open flames.
-In case of accidental inhalation or exposure to this compound, seek medical attention immediately.
Last Update:2024-04-09 02:00:44